Severe Anemia Due to Cold Agglutinin Syndrome in a COVID-19 Patient with IgM Monoclonal Gammopathy of Undetermined Significance Successfully Treated with Corticosteroids

Autor:	Tsukamoto, Yutaka, Umeda, Masataka, Muto, Yuko, Sugimoto, Takashi, Yamauchi, Momoko, Ando, Koji, Ariyoshi, Koya
Rok vydání:	2022
Předmět:	corticosteroid COVID-19 General Medicine Monoclonal Gammopathy of Undetermined Significance Immunoglobulin M Adrenal Cortex Hormones Internal Medicine Humans Female cold agglutinin syndrome Anemia Hemolytic Autoimmune autoimmune hemolytic anemia Cryoglobulins Aged
Zdroj:	Internal Medicine. 61:1789-1793
ISSN:	1349-7235 0918-2918
Popis:	Secondary cold agglutinin syndrome (CAS) is autoimmune hemolytic anemia secondary to infections and lymphoid disorder. We here report the first Asian case of CAS secondary to novel coronavirus disease 2019 (COVID-19). A 72-year-old Japanese woman presented with a 2-week history of dyspnea and cough, and laboratory data revealed severe hemolytic anemia with a hemoglobin level of 4.7 g/dL. She was diagnosed with COVID-19, CAS, and monoclonal gammopathy of undetermined significance (MGUS). The anemia responded to corticosteroids administered for COVID-19 and required maintenance therapy. Although corticosteroids are not a standard therapy for CAS, they might be effective for CAS secondary to COVID-19 complicated with MGUS. Internal Medicine, 61(11), pp. 1789-1793; 202
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcc0b8194ee8376ed00753780a93e4e https://doi.org/10.2169/internalmedicine.8647-21 Zobrazit plný text záznamu