Study on existence of inflammation in the myocardium in unequivocal acute traumatic deaths
| Autor: | P.A.S. Edirisinghe, I.D.G. Kitulwatte |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Myocarditis Adolescent Poison control Autopsy Inflammation Gastroenterology Pathology and Forensic Medicine Gross examination Young Adult Internal medicine Age related Injury prevention medicine Humans Prospective Studies Child Forensic Pathology Cause of death business.industry Myocardium Accidents Traffic Age Factors General Medicine Organ Size medicine.disease Child Preschool Wounds and Injuries Female medicine.symptom business Law |
| Zdroj: | Journal of forensic and legal medicine. 75 |
| ISSN: | 1878-7487 |
| Popis: | Background Over-diagnosis of myocarditis is possible, where presence of scant/negligible inflammatory foci are interpreted as active myocarditis in autopsy cases. A Prospective descriptive study on 100 young healthy individuals who died of known sudden traumatic causes was performed to study the existence, frequency and severity of inflammatory foci in myocardium of a normal population who died suddenly of acute trauma, in order to develop an autopsy diagnostic criteria. Results Out of 100 hearts, 48 had scant inflammatory foci. Thirteen had mild inflammation and three with moderate inflammation. Presence of scant inflammation was significantly associated with the age of the individual (P = 0.0182). However, the presence or severity of inflammation did not show any significant association with the clinical symptoms (P = 0.4924), gross pathology (P = 0.3954) or weight of the heart (P = 0.3109). Conclusions Presence of scant inflammation in the myocardium is a common occurrence and it may be an age related change, which cannot account for the cause of death. Much severe forms of myocarditis with no clinically apparent picture could exist among young individuals. Thus, in the absence of other causes of death, conclusion of myocarditis as a cause of death in these cases needs a careful evaluation of other positive signs. |
| Databáze: | OpenAIRE |
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