Monitoring the efficiency of detoxification therapy in newborn infants with ventilatorassociated pneumonia

Autor:	G. M. Dementyeva, E. S. Keshishian, E. S. Vozdvizhenskaya, E. A. Yuryeva, M. V. Kushnareva
Rok vydání:	2016
Předmět:	medicine.medical_specialty business.industry Detoxification therapy fluorometry medicine.disease Pediatrics RJ1-570 Pneumonia newborn infants Pediatrics Perinatology and Child Health medicine pneumonia business Intensive care medicine albumin endotoxicosis
Zdroj:	Rossijskij Vestnik Perinatologii i Pediatrii, Vol 61, Iss 1, Pp 37-41 (2016)
ISSN:	2500-2228 1027-4065
Popis:	The efficiency of a fluorometric method for measuring the total and effective concentrations albumin and toxicity index in capillary blood was investigated in 60 neonates having a birth weight of 864 to 4020 g and bacterial pneumonia to evaluate the severity of endogenous toxicosis and to monitor detoxification therapy. The method can rapidly, objectively, and exactly estimate the adequately enhanced albumin functional activity that corresponds to an increase in total and effective blood albumin concentrations and a decrease in toxicity index by 20% or more. To alleviate the symptoms of pneumonia and infectious toxicity and to normalize both absolute albumin values and toxicity index are a ground to discontinue detoxification therapy. The method can substantially improve the objective monitoring of the efficiency of therapy for infectious toxicosis that complicates the course of bacterial pneumonia in newborns and ensure their adequate treatment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db85570ddfdeece02f97079564ee623 https://doi.org/10.21508/1027-4065-2016-61-1-37-41 Zobrazit plný text záznamu