Total White Blood Cell Count is Associated with Arterial Stiffness Among Hypertensive Patients

Autor: Min Huang, Fajiu Li, Si Chen, Min Liu, Wei Qin, Juanjuan Wu, Ying Chen, Jinnan Zhong, Qian Zhao, Bingzhu Hu
Rok vydání: 2022
Předmět:
Zdroj: Angiology.
ISSN: 1940-1574
Popis: The association between white blood cell (WBC) count and arterial stiffness in patients with hypertension is not well-documented. We aimed to examine the relationships of total WBC count with arterial stiffness and risk of macrovascular damage in hypertensive patients. A total of 631 hypertensive adults (mean age: 65.6 years) were included in the present study. Arterial stiffness was determined by brachial-ankle pulse wave velocity (baPWV) and ankle-brachial index (ABI). Macrovascular damage was defined as baPWV >1.8 m/s or ABI trend = .010) and reduced ABI (β = −.027; 95% CI: −.046, −.008; Ptrend = .005), as compared with those in the first tertile. The association was similar in different subgroups. In addition, elevated total WBC count was related to a greater risk of macrovascular damage, as indicated by baPWV >1.8 m/s (OR = 1.86; 95% CI: 1.15, 2.99, comparing the extreme tertiles). Our data suggest that elevated total WBC count was related to arterial stiffness among individuals with hypertension.
Databáze: OpenAIRE