Celiac Dietary Adherence Test and Standardized Dietician Evaluation in Assessment of Adherence to a Gluten-Free Diet in Patients with Celiac Disease

Autor: Katarzyna Gładyś, Marek Guzek, Sylwia Małgorzewicz, Krystian Adrych, Jolanta Anna Dardzińska
Rok vydání: 2020
Předmět:
Male
Tissue transglutaminase
Biopsy
Disease
Gliadin
0302 clinical medicine
030212 general & internal medicine
chemistry.chemical_classification
Nutrition and Dietetics
biology
Middle Aged
dietitian assessment
adherence to a gluten-free diet
Female
030211 gastroenterology & hepatology
lcsh:Nutrition. Foods and food supply
Adult
medicine.medical_specialty
Adolescent
Duodenum
Duodenal biopsy
lcsh:TX341-641
Gliadin peptide
Diet Surveys
Article
Diet
Gluten-Free
Young Adult
03 medical and health sciences
GTP-Binding Proteins
Internal medicine
standardized dietary evaluation
medicine
Humans
Protein Glutamine gamma Glutamyltransferase 2
In patient
Aged
Autoantibodies
Transglutaminases
business.industry
nutritional and metabolic diseases
Reproducibility of Results
refractory celiac disease
Gluten
digestive system diseases
Celiac Disease
chemistry
Registered dietitian
biology.protein
Patient Compliance
Gluten free
business
Food Science
Zdroj: Nutrients, Vol 12, Iss 2300, p 2300 (2020)
Nutrients
Volume 12
Issue 8
ISSN: 2072-6643
DOI: 10.3390/nu12082300
Popis: Adherence to a gluten-free diet (GFD) is currently the mainstay of treatment strategy for celiac disease (CD). The aim of our study was measuring a GFD adherence in CD patients using two newly validated methods of dietary assessment&mdash
Standardized Dietician Evaluation (SDE) and the Celiac Dietary Adherence Test (CDAT). Ninety-two adults with CD were evaluated by a registered dietitian with extensive experience with the use of SDE and CDAT. Duodenal biopsy was performed and blood was drawn for serum anti-endomysial, anti-deamidated gliadin peptide and anti-tissue transglutaminase antibodies in forty four of those patients. The results of CDAT and SDE were very convergent, but SDE scores better correlated with serologic and histologic findings. As many as 24&ndash
52% of study participants did not adhere well enough to a GFD. Insufficient adherence to a GFD in CD patients is still a significant problem. The knowledge about gluten content in food ingredients and additives is very low among adults with CD. SDE is the most accurate method in assessing compliance with a GFD and is especially helpful in determining hidden sources of gluten. The CDAT may be a fast tool for screening for a GFD adherence in CD patients.
Databáze: OpenAIRE
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