0716. Does intravenous iron induce oxydative stress in critically ill patients? A comparison with healthy volunteers

Autor: Xavier Duval, G. Dufour, Camille Couffignal, Emmanuel Rineau, Fathi Driss, Pascale Piednoir, Clémentine Schilte, Sigismond Lasocki
Rok vydání: 2014
Předmět:
Zdroj: Intensive Care Medicine Experimental
ISSN: 2197-425X
DOI: 10.1186/2197-425x-2-s1-p47
Popis: Anaemia is frequent in critically ill patients. Iron deficiency, secondary to blood losses or prior to admission, is in part responsible for this anaemia. Iron may thus be proposed to critically ill patients (CI). However, iron may promote oxidative stress, which is potentially deleterious. In a mouse model, we previously demonstrated that iron induces less oxidative stress in inflamed mice than in control ones [1], but no data are available in the CI.
Databáze: OpenAIRE