Prognostic value of SUVmax in breast cancer and comparative analyses of molecular subtypes
| Autor: | Seungju Lee, Youn Joo Jung, Chang Shin Jung, Moon Il Lee, Dong-Il Kim, Hyun Yul Kim, Kyoungjune Pak, Seong Jang Kim, Seok Kyung Kang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty Axillary lymph nodes Breast Neoplasms Immunophenotyping Breast cancer breast cancer Predictive Value of Tests Survival prognosis Internal medicine medicine Humans In patient prognostic value medicine.diagnostic_test business.industry Hazard ratio SUVmax General Medicine medicine.disease Primary tumor meta-analysis medicine.anatomical_structure Positron emission tomography Meta-analysis Female business Systematic Review and Meta-Analysis Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | Background: To assess the prognostic capability of the maximum standardized uptake values (SUVmax) measured in the primary tumor and axillary lymph nodes (ALNs) by pretreatment fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography and analyze outcomes according to the molecular breast cancer subtypes. Methods: The databases were systematically searched using keywords for breast cancer, positron emission tomography/computed tomography, and SUVmax; the extracted studies reported at least 1 form of survival data, event-free survival (EFS) and overall survival. Comparative analyses of the pooled hazard ratios (HRs) for EFS and overall survival were performed to assess their correlations with SUVmax. The pooled HR was estimated using random-effects model according to the results of heterogeneity. Results: Thirteen eligible studies comprising 3040 patients with breast cancer were included. The pooled HRs of high SUVmax in the primary tumor and ALN were 3.01 (95% CI 1.83–4.97, P |
| Databáze: | OpenAIRE |
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