Forgotten Right Ventricle in Pediatric Dilated Cardiomyopathy
| Autor: | Naglae Abd El Rahman, Inas Abd El Satar, Mohamed Abd El Rahman, Sonia A. El Saeidi, Wael Attia, Doaa Abd El Aziz, Hossam Samir Ibrahim, Hala Agha, Fatma El Zahraa Mostafa, Gaser Abd El Mohsen, Zeinab Salah |
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| Rok vydání: | 2017 |
| Předmět: |
Cardiomyopathy
Dilated Male medicine.medical_specialty Heart Ventricles Ventricular Dysfunction Right Diastole Speckle tracking echocardiography 030204 cardiovascular system & hematology Doppler imaging Ventricular Function Left Ventricular Dysfunction Left 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Prospective Studies 030212 general & internal medicine Child Isovolumic acceleration Receiver operating characteristic business.industry Dilated cardiomyopathy medicine.disease Echocardiography Doppler Cardiac surgery medicine.anatomical_structure Ventricle Case-Control Studies Child Preschool Pediatrics Perinatology and Child Health Ventricular Function Right Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Pediatric Cardiology. 38:819-827 |
| ISSN: | 1432-1971 0172-0643 |
| DOI: | 10.1007/s00246-017-1588-7 |
| Popis: | To evaluate the right ventricular (RV) function in relation to that of the left ventricle (LV) in patients with dilated cardiomyopathy (DCM). Echocardiographic examination was done using tissue Doppler imaging (TDI) and two-dimensional speckle tracking echocardiography (2D-STE) for 32 pediatric patients with DCM comparing them to another 32 normal matched controls. The global longitudinal strain (GLS) derived from 2D-STE was used to reflect the LV systolic function. Tricuspid annular plan systolic excursion (TAPSE) and the following RV TDI derived indexes: peak systolic velocity (S′), peak early diastolic velocity E′, peak late diastolic velocity A', isovolumic acceleration (IVA) and myocardial performance index (MPI) were measured. RV had significant systolic and diastolic dysfunction; TAPSE, S′ velocity, IVA, peak early diastolic velocity (E′) and peak early diastolic velocity/peak late diastolic velocity (E′/A′) ratio were significantly decreased while MPI was significantly prolonged compared to controls. Moreover, TAPSE, S′, IVA, E′, E′/A′ and RV MPI were significantly correlated to LV GLS. For prediction of LV dysfunction among patients, the area under the receiver operating characteristic curve was 0.98 for RV MPI, 0.906 for RV IVA. For identifying severe LV dysfunction; RV MPI > 0.29 had 100% sensitivity and 93.7% specificity, while the RV IVA ≤ 3 had 84.4% sensitivity and 90.6% specificity. In pediatric patients with DCM the RV systolic and diastolic functions are affected beside the LV dysfunction. Non-conventional echocardiographic evaluation of RV function is recommended in among this cohort. |
| Databáze: | OpenAIRE |
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