Marine Natural Products as Leads against SARS-CoV-2 Infection

Autor:	Bhuwan Khatri Chhetri, Philip R. Tedbury, Anne Marie Sweeney-Jones, Luke Mani, Katy Soapi, Candela Manfredi, Eric Sorscher, Stefan G. Sarafianos, Julia Kubanek
Rok vydání:	2022
Předmět:	Pharmacology Biological Products Complementary and alternative medicine SARS-CoV-2 Organic Chemistry Drug Discovery Pharmaceutical Science Molecular Medicine Humans Epithelial Cells Antiviral Agents Analytical Chemistry COVID-19 Drug Treatment
Zdroj:	Journal of natural products. 85(3)
ISSN:	1520-6025
Popis:	Since early 2020, disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic, causing millions of infections and deaths worldwide. Despite rapid deployment of effective vaccines, it is apparent that the global community lacks multipronged interventions to combat viral infection and disease. A major limitation is the paucity of antiviral drug options representing diverse molecular scaffolds and mechanisms of action. Here we report the antiviral activities of three distinct marine natural products─homofascaplysin A (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d93969004916103e183635d396b9d02 https://pubmed.ncbi.nlm.nih.gov/35290044 Zobrazit plný text záznamu