Oncological results at 2 years after robotic radical prostatectomy – the Romanian experience
| Autor: | Iulia Andras, Ioan Coman, Dan Vasile Stanca, Radu-Tudor Coman, Flavia Epure, Nicolae Crisan, Horia Logigan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Biochemical recurrence
medicine.medical_specialty Surgical margin Original Paper business.industry Prostatectomy Pathological staging medicine.medical_treatment 030232 urology & nephrology Urology Robotic Surgical Procedures General Medicine medicine.disease prostatic neoplasms radical prostatectomy 03 medical and health sciences Prostate cancer 0302 clinical medicine 030220 oncology & carcinogenesis robotic surgical procedures Medicine Robotic surgery Radiology Positive Surgical Margin business |
| Zdroj: | Central European Journal of Urology |
| ISSN: | 2080-4873 2080-4806 |
| Popis: | INTRODUCTION To assess the oncological outcomes of robotic radical prostatectomy in a country where there are no on-going national screening programs for prostate cancer. MATERIAL AND METHODS Between November 2009 and November 2014, 220 robotic radical prostatectomies were performed at our Robotic Surgery Center. We already have the complete data for the 2-year follow-up of the first 105 patients, who were therefore included in the study group. Pre-operative (age, prostate-specific antigen, body-mass index, prostate volume, clinical staging, biopsy characteristics), post-operative (surgical technique, surgical margin status, lymph node status, pathological stage, Gleason score) and follow-up parameters (biochemical recurrence) were assessed. RESULTS The global rate of positive surgical margins was 34.3%, with rates of 17.2% in stage pT2 and 55.3% in stage pT3. The most frequent localization for positive surgical margins was at the base and apex of the prostate. The positive surgical margins rate was correlated with the pre-operative prostate-specific antigen, clinical and pathological Gleason score, lymph node status and the number of positive biopsy cores. The rate of biochemical recurrence at the 2-year follow-up was 11.8%. The most important predictors for the biochemical recurrence were the positive surgical margins, pathological staging and Gleason score on the prostatectomy specimen. CONCLUSIONS Robotic surgery is validated by the oncological results at medium follow-up (2 years) for localized and locally advanced prostate cancer, even in countries where there is no on-going national screening program. |
| Databáze: | OpenAIRE |
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