Abdominal ultrasound and clinicopathologic findings in 22 cats with exocrine pancreatic insufficiency
| Autor: | Joerg M. Steiner, Gwendolyn J. Levine, Dominique G. Penninck, Cary M. Springer, Mylène Auger, Constance Fazio, John F. Griffin |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pathology
medicine.medical_specialty Veterinary medicine diarrhea pancreatitis Standard Article Cat Diseases Feces Endocrinology SF600-1100 medicine Animals Trypsin feline Exocrine pancreatic insufficiency pancreatic duct Pancreas Retrospective Studies Pancreatic duct CATS General Veterinary business.industry Ultrasound Echogenicity medicine.disease Standard Articles Diarrhea EPI medicine.anatomical_structure fTLI Cats Pancreatitis Exocrine Pancreatic Insufficiency SMALL ANIMAL medicine.symptom weight loss business |
| Zdroj: | Journal of Veterinary Internal Medicine Journal of Veterinary Internal Medicine, Vol 35, Iss 6, Pp 2652-2661 (2021) |
| ISSN: | 1939-1676 0891-6640 |
| Popis: | Background Awareness of exocrine pancreatic insufficiency (EPI) in cats has increased since the development of an assay for feline trypsin-like immunoreactivity (fTLI). Ultrasound findings in cats with EPI have only been reported rarely and described as nonspecific. Hypothesis/objectives To describe the ultrasonographic findings, clinical signs, and concurrent diseases in cats with EPI. Animals Twenty-two client-owned cats with EPI. Methods Multicenter retrospective descriptive study including cats with serum fTLI concentration ≤8 μg/L and an abdominal ultrasound examination performed within 6 weeks of fTLI measurement. Sonographic measurements of maximal pancreatic thickness and maximal pancreatic duct diameter as well as ratios of pancreatic duct diameter to pancreatic thickness were obtained. Additional sonographic findings, concurrent conditions, and clinical signs were recorded. Results The most common clinical sign was weight loss (15/22 cats). Chronic enteropathy was the most common concurrent disease (13/22 cats). In 39% of cats, the pancreas had minimal or no sonographic alterations. Pancreatic duct dilatation (>2.5 mm), pancreatic duct tortuosity with variable diameter, or both were seen in 6/13 cats. The pancreatic parenchyma was subjectively thin in 6 cats. A significant relationship was found between subjectively thin pancreatic parenchyma and increased pancreatic duct size : pancreatic thickness ratio (P = .004). Diffuse gastrointestinal dilatation with echogenic content was observed in 8/22 cats. Conclusion Exocrine pancreatic insufficiency often causes minimal to no sonographic pancreatic changes. Nonetheless, the findings of thin pancreatic parenchyma, pancreatic duct dilatation, or diffuse small intestinal dilatation with echogenic contents in cats with unexplained weight loss or unformed feces should raise clinical suspicion for EPI. |
| Databáze: | OpenAIRE |
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