Survival in Acute Non-Lymphocytic Leukaemia following Breast Cancer
| Autor: | F F Holmes, S D Kaster |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Oncology medicine.medical_specialty Time Factors Myeloid medicine.medical_treatment Breast Neoplasms Neoplasms Multiple Primary 03 medical and health sciences 0302 clinical medicine Breast cancer Risk Factors hemic and lymphatic diseases Statistical significance Internal medicine Adjuvant therapy Humans Medicine Combined Modality Therapy 030212 general & internal medicine Survival rate Aged Chemotherapy business.industry Age Factors General Medicine Middle Aged medicine.disease 030227 psychiatry Survival Rate Leukemia Myeloid Acute Leukemia medicine.anatomical_structure Female business Research Article |
| Zdroj: | Journal of the Royal Society of Medicine. 83:693-695 |
| ISSN: | 1758-1095 0141-0768 |
| Popis: | Acute non-lymphocytic leukaemia (ANLL) occurs with increased frequency in women with previously diagnosed breast cancer. Adjuvant radiotherapy and chemotherapy are related to this increase. We studied the interrelationships among age at breast cancer diagnosis, interval to ANLL diagnosis, and survival in 54 women of whom 11 were from Kansas and 43 were from two other published series. Median age at breast cancer diagnosis was 50.5 years, median interval to ANLL diagnosis was 4.8 years, and median survival after ANLL diagnosis was 2.2 months. Increasing age was associated with a decrease of the interval to ANLL diagnosis just short of statistical significance (P=0.0591). There was no association of survival with either age or the interval to ANLL diagnosis. With an increase in the use of adjuvant therapy in breast cancer there is a need to identify women at greatest risk of subsequently developing ANLL, at present not possible. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|