Multicenter Survey of Routine Determinations of Resistance of Helicobacter pylori to Antimicrobials over the Last 20 Years (1990 to 2009) in Belgium
| Autor: | Jean-Baptiste Vanderpas, Patrick Bontems, E. De Koster, Alain Burette, Ruffin Ntounda, C. Van den Borre, V. Y. Miendje Deyi, Samy Cadranel |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Microbiology (medical) Pediatrics medicine.medical_specialty Adolescent Biopsy Population Microbial Sensitivity Tests Helicobacter Infections Young Adult Antibiotic resistance Sex Factors Belgium Clarithromycin Internal medicine Drug Resistance Bacterial medicine Humans education Child Aged Aged 80 and over education.field_of_study biology Helicobacter pylori business.industry Age Factors Infant Bacteriology Amoxicillin Middle Aged biology.organism_classification Antimicrobial Anti-Bacterial Agents Ciprofloxacin Metronidazole Gastric Mucosa Child Preschool Female Erratum business medicine.drug |
| Popis: | We analyzed the rates of antimicrobial resistance of Helicobacter pylori strains isolated from patients from 1990 to 2009 and identified risk factors associated with resistance. Gastric biopsy specimens were collected from several digestive disease centers in Brussels, Belgium. We routinely performed antimicrobial susceptibility testing for clarithromycin (CLR), metronidazole, amoxicillin, tetracycline, and ciprofloxacin. Evaluable susceptibility testing was obtained for 9,430 strains isolated from patients who were not previously treated for Helicobacter pylori infection (1,527 isolates from children and 7,903 from adults) and 1,371 strains from patients who were previously treated (162 isolates from children and 1,209 from adults). No resistance to amoxicillin was observed, and tetracycline resistance was very rare ( |
| Databáze: | OpenAIRE |
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