Occurrence of plasmidic AmpC β-lactamase in a Salmonella Typhimurium isolate of equine origin: First report of CMY-2 in animals in Argentina

Autor: E.C. Mercado, José Alejandro Di Conza, Gabriel Osvaldo Gutkind, Johana E. Dominguez
Rok vydání: 2015
Předmět:
Zdroj: Journal of Global Antimicrobial Resistance. 3:315-316
ISSN: 2213-7165
DOI: 10.1016/j.jgar.2015.09.006
Popis: The increase in transferable resistance to third-generation cephalosporins in zoonotic Salmonella constitutes a serious public health threat. Resistance to third-generation cephalosporins is mainly due to acquisition of genes encoding extended-spectrum β-lactamases or AmpC β-lactamases. These genes are mainly plasmid-encoded and are transferable into various serovars of Salmonella and other enteric bacteria. CMY-type enzymes are the most common plasmid-mediated AmpC β-lactamase among Enterobacteriaceae [1]. A variety of plasmids have been shown to carry the blaCMY-2 gene and some of them may be associated with particular Salmonella serotypes from environmental sources. Although CMY-2-producing Salmonella have been found in humans and animals in many countries and regions, isolates from animals has not been previously reported in Argentina. Fil: Dominguez, Johana Elizabeth. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Gutkind, Gabriel Osvaldo. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Di Conza, José Alejandro. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Mercado, Elsa Cristina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina
Databáze: OpenAIRE
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