Benign Leydig cell tumour and germ cell carcinoma in situ in a young man with gynaecomastia
| Autor: | M. S. Mann, J. P. Hopewell, R. S. Fink, J. Ginsburg |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Urinary system Leydig cell tumour Testicular Neoplasms Internal medicine Carcinoma medicine Humans Histological examination business.industry Carcinoma in situ Germinal cell Right testis General Medicine medicine.disease medicine.anatomical_structure Endocrinology Gynecomastia business Carcinoma in Situ Germ cell Leydig Cell Tumor Research Article |
| Zdroj: | Postgraduate Medical Journal. 60:66-69 |
| ISSN: | 1469-0756 0032-5473 |
| DOI: | 10.1136/pgmj.60.699.66 |
| Popis: | Summary A 21-year-old man presented with a 16-year history of recurrent pyrexial episodes and a 5-year history of gynaecomastia. Blood and urinary oestrogen levels were elevated and a mass was found in the upper pole of a retractile right testis. After orchidectomy, oestrogen levels fell, gynaecomastia regressed and the pyrexial episodes ceased. Histological examination of the right testis showed a benign Leydig cell tumour in the upper pole and a germinal cell carcinoma in situ in the remaining part of the testis. Thus a potentially lethal condition was detected at an early pre-malignant phase by virtue of a benign, endocrinologically active tumour. This would seem to be the first report of the co-existence of a Leydig cell tumour and germ cell carcinoma in the same testis. |
| Databáze: | OpenAIRE |
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