Rapid and Convenient Conversion of Nitroarenes to Anilines under Microwave Conditions Using Non-precious Metals in Mildly Acidic Medium
| Autor: | S. Shaun Murphree, Corey S. Keenan |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Aqueous solution
010405 organic chemistry Organic Chemistry Inorganic chemistry chemistry.chemical_element Zinc 010402 general chemistry 01 natural sciences 0104 chemical sciences chemistry.chemical_compound Aniline chemistry Microwave chemistry Yield (chemistry) Ammonium chloride Methanol Microwave |
| DOI: | 10.6084/m9.figshare.4806979.v1 |
| Popis: | Nitroarenes are reduced to the corresponding aniline derivatives using iron or zinc under mild conditions under microwave heating conditions. Mild acidity is provided by ammonium chloride in an aqueous methanol medium. The conditions are tolerant to other functional groups, with the exception of bromoalkyl derivatives, which yield complex reaction mixtures; otherwise, yields are generally quite high (80–99%). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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