Clinical Utility of Biosensing Platforms for Confirmation of SARS-CoV-2 Infection

Autor: Thi-Thu Pham, My-Van Tieu, Le Minh Tu Phan, Sungbo Cho
Rok vydání: 2021
Předmět:
Coronavirus disease 2019 (COVID-19)
Computer science
viruses
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Point-of-care testing
Clinical Biochemistry
RT-PCR
Biomedical Engineering
Enzyme-Linked Immunosorbent Assay
Review
Biosensing Techniques
02 engineering and technology
Diagnostic tools
Analytical Chemistry
03 medical and health sciences
COVID-19 Testing
Pandemic
Animals
Humans
Instrumentation
Engineering (miscellaneous)
RT-LAMP
030304 developmental biology
Strategic planning
0303 health sciences
optical biosensor
lab-in-a-tube
SARS-CoV-2
lateral flow assay
Electrochemical Techniques
Equipment Design
General Medicine
Nucleic acid amplification technique
021001 nanoscience & nanotechnology
nucleic acid amplification
electrochemical biosensor
Risk analysis (engineering)
Point-of-Care Testing
Clinical diagnosis
ELISA
Colorimetry
COVID-19 clinical diagnostics
0210 nano-technology
Nucleic Acid Amplification Techniques
TP248.13-248.65
Biotechnology
Zdroj: Biosensors
Biosensors, Vol 11, Iss 167, p 167 (2021)
ISSN: 2079-6374
DOI: 10.3390/bios11060167
Popis: Despite collaborative efforts from all countries, coronavirus disease 2019 (COVID-19) pandemic has been continuing to spread globally, forcing the world into social distancing period, making a special challenge for public healthcare system. Before vaccine widely available, the best approach to manage severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is to achieve highest diagnostic accuracy by improving biosensor efficacy. For SARS-CoV-2 diagnostics, intensive attempts have been made by many scientists to ameliorate the drawback of current biosensors of SARS-CoV-2 in clinical diagnosis to offer benefits related to platform proposal, systematic analytical methods, system combination, and miniaturization. This review assesses ongoing research efforts aimed at developing integrated diagnostic tools to detect RNA viruses and their biomarkers for clinical diagnostics of SARS-CoV-2 infection and further highlights promising technology for SARS-CoV-2 specific diagnosis. The comparisons of SARS-CoV-2 biomarkers as well as their applicable biosensors in the field of clinical diagnosis were summarized to give scientists an advantage to develop superior diagnostic platforms. Furthermore, this review describes the prospects for this rapidly growing field of diagnostic research, raising further interest in analytical technology and strategic plan for future pandemics.
Databáze: OpenAIRE
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