Maternal Near Miss in Patients with Systemic Lupus Erythematosus
| Autor: | Arlley Cleverson Belo da Silva, Sue Yazaki Sun, Felipe Favorette Campanharo, Letícia Tiemi Morooka, José Guilherme Cecatti, Rosiane Mattar |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics. 45:011-020 |
| ISSN: | 1806-9339 0100-7203 |
| DOI: | 10.1055/s-0042-1759633 |
| Popis: | Introduction: Systemic lupus erythematosus (SLE) may cause irreversible organ damage. Pregnancy with coexisting SLE may have severe life-threatening risks. Severe maternal morbidities (SMM) include maternal death, maternal near miss (MNM), and potentially life-threatening conditions (PLTC). This study aimed to determine the prevalence of SMM in patients with SLE and analyze the parameters that contributed to cases of greater severity. Methods: This is a cross-sectional retrospective study from analysis of data retrieved from medical records of pregnant women with SLE treated at São Paulo Hospital , Brazil, from 2005 to 2015. The pregnant women were divided in control group without complications, group with PLTC, and group with MNM. Results: Out of 149 pregnancies, there were 14 cases of MNM (9.4%), 56 cases of PLTC (37.6%), and no maternal death. The maternal near miss rate was 112.9 per 1,000 live births. The majority of PLTC (83.9%) and MNM (92.9%) cases had preterm deliveries with statistically significant increased risk compared with control group [p=0.0042; OR (95% CI): 12.05 (1.5-96.6) for MNM group and p=0.0001; OR (95% CI): 4.84 (2.2-10.8) for PLTC group]. SMM increases the risk of longer hospitalization [pConclusion: SLE was significantly associated with severe maternal morbidity, longer hospitalizations, and increased risk of poor obstetric and neonatal outcomes, such as prematurity, neonatal death, miscarriage and fetal loss. |
| Databáze: | OpenAIRE |
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