Pupillometry measures of autonomic nervous system regulation with advancing age in a healthy pediatric cohort
| Autor: | Kristen Kelly, Saajidha Rizvydeen, Sara M. Hockney, Justin J. Warner, Bradley J. Scher, Stephen Joza, Thomas Bielawiec, Tracey M. Stewart, Debra E. Weese-Mayer, Anna S. Kenny, Aaron Charnay, Samantha C. Gordon, Drew Simon, Lynne Trojanowski, Sally F. Vitez, Amy Zhou, Grace Niewijk, Michelle Price, Molly Winston, Emma C. Dunne, Lena J. Volpe, David W. Reed, Nicholas J. Volpe, Cia Panicker, Casey M. Rand, Cindy D. Brogadir, Cara Coleman, Gigi Buniao, Allison Bradley, Brooke A. Pigneri |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Neurology Adolescent genetic structures Health Status 030204 cardiovascular system & hematology Stimulus (physiology) Autonomic Nervous System Reflex Pupillary Constriction Cohort Studies Young Adult 03 medical and health sciences 0302 clinical medicine Ophthalmology Concussion medicine Humans Child Endocrine and Autonomic Systems business.industry Age Factors Pupil medicine.disease Autonomic nervous system Cross-Sectional Studies Child Preschool Cohort Female Neurology (clinical) Analysis of variance business Photic Stimulation 030217 neurology & neurosurgery Pupillometry |
| Zdroj: | Clinical Autonomic Research. 30:43-51 |
| ISSN: | 1619-1560 0959-9851 |
| Popis: | To determine if variables of the pupillary light response mature with age and sex in a healthy pediatric cohort and the utility of pupillometry in assessment among pediatric participants. After 1 min in a dark room to establish baseline, pupillometry was performed on 323 healthy, pediatric participants (646 eyes; 2–21 years; 175 females). Variables included initial pupil diameter, pupil diameter after light stimulus, percent pupillary constriction, latency to onset of constriction, average constriction velocity, maximum constriction velocity, average dilation velocity, and time from light stimulus to 75% of the initial pupil diameter. Data analyses employed ANOVAs and non-linear regressions. Analyses of age group differences revealed that participants 12–21 years old had a larger initial pupil diameter and pupil diameter after light stimulus, with males aged 12–18 years demonstrating a larger pupil diameter than all younger participants (ps |
| Databáze: | OpenAIRE |
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