Primary Pediatric Osteosarcoma of the Skull
| Autor: | Louis Morales, Hong Holly Zhou, Emily J. Kirby |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Male
musculoskeletal diseases medicine.medical_specialty Adolescent Biopsy Skull Neoplasms Malignancy Diagnosis Differential Lesion Antineoplastic Combined Chemotherapy Protocols medicine Humans Combined Modality Therapy Osteosarcoma medicine.diagnostic_test Retinoblastoma business.industry Magnetic resonance imaging General Medicine Plastic Surgery Procedures medicine.disease Magnetic Resonance Imaging Skull medicine.anatomical_structure Otorhinolaryngology Surgery Radiology medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | Journal of Craniofacial Surgery. 22:2399-2405 |
| ISSN: | 1049-2275 |
| DOI: | 10.1097/scs.0b013e318231fe9b |
| Popis: | A 16-year-old adolescent boy presented with osteosarcoma of the left parieto-occipital bone with no history of radiation, Paget disease, or retinoblastoma. The tumor presented as a painless lump, which he attributed to minor trauma 5 months before presentation. Biopsy of the lesion was inconclusive. Complete surgical resection was attained. Pathology revealed a diagnosis of osteosarcoma, grade 1 to 2/3. Adjuvant chemotherapy commenced after tumor resection. Primary pediatric osteosarcoma of the skull is an exceedingly rare malignancy, with only a handful of cases ever reported. Complete surgical resection with negative margins is the key to optimizing disease-free survival. Adjuvant chemotherapy is recommended for high-grade tumors and in cases of incomplete resection. |
| Databáze: | OpenAIRE |
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