Striatal dopamine synthesis capacity reflects smartphone social activity
| Autor: | Lieke Hofmans, Jessica I. Määttä, Roshan Cools, Andrew Westbrook, Ruben van den Bosch, Arko Ghosh |
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| Přispěvatelé: | Ontwikkelingspsychologie (Psychologie, FMG) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Striatal dopamine Dopamine synthesis Science Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13] 02 engineering and technology Behavioral neuroscience Article Behavioral variability Correlation 03 medical and health sciences All institutes and research themes of the Radboud University Medical Center Dopamine medicine Multidisciplinary Putamen Social activity 021001 nanoscience & nanotechnology Biological sciences 030104 developmental biology 0210 nano-technology Psychology Neuroscience 170 000 Motivational & Cognitive Control medicine.drug |
| Zdroj: | iScience, Vol 24, Iss 5, Pp 102497-(2021) iScience, 24(5) iScience, 24, 5 iScience, 24(5):102497. Elsevier Inc. iScience iScience, 24 |
| ISSN: | 2589-0042 |
| Popis: | Summary Striatal dopamine and smartphone behavior have both been linked with behavioral variability. Here, we leverage day-to-day logs of natural, unconstrained smartphone behavior and establish a correlation between a measure of smartphone social activity previously linked with behavioral variability and a measure of striatal dopamine synthesis capacity using [18F]-DOPA PET in (N = 22) healthy adult humans. Specifically, we find that a higher proportion of social app interactions correlates with lower dopamine synthesis capacity in the bilateral putamen. Permutation tests and penalized regressions provide evidence that this link between dopamine synthesis capacity and social versus non-social smartphone interactions is specific. These observations provide a key empirical grounding for current speculations about dopamine's role in digital social behavior. Graphical abstract Highlights • Putamen dopamine synthesis capacity correlates with smartphone social app use. • The correlation parallels a prior link between social app use and motor variability. • It is selective to social app use, controlling for multiple smartphone use factors. Behavioral neuroscience; Biological sciences; Neuroscience |
| Databáze: | OpenAIRE |
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