Relationship of healthy vascular aging with lifestyle and metabolic syndrome in the general Spanish population. The EVA study
| Autor: | Rosario Alonso-Domínguez, Leticia Gomez-Sanchez, Manuel A. Gómez-Marcos, José I. Recio-Rodríguez, Jesus Gonzalez-Sanchez, Marta Gomez-Sanchez, Luis García-Ortiz, Natalia Sánchez-Aguadero, M. Carmen Patino-Alonso |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Aging medicine.medical_specialty Waist Adolescent Disease 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Humans Medicine Child Life Style Abdominal obesity Metabolic Syndrome Framingham Risk Score business.industry General Medicine Middle Aged medicine.disease Spanish population Cross-Sectional Studies Blood pressure Child Preschool Female Vascular aging medicine.symptom Metabolic syndrome business |
| Zdroj: | Revista Española de Cardiología (English Edition). 74:854-861 |
| ISSN: | 1885-5857 |
| Popis: | Our objective was to study the relationship of healthy vascular aging (HVA) with lifestyle and the components of metabolic syndrome. We also analyzed the differences between chronological age and heart age (HA) and vascular age (VA) in the Spanish adult population without cardiovascular disease.This descriptive cross-sectional study selected 501 individuals without cardiovascular disease (mean age, 55.9 years; 50.3% women) via random sampling stratified by age and sex. HA was estimated with the Framingham equation, whereas VA was estimated with the VaSera VS-1500 device. HVA was defined as a5-year difference between the chronological age and the HA or VA and the absence of a vascular lesion, hypertension, and diabetes mellitus.Compared with the chronological age, the mean HA and VA were 2.98±10.13 and 3.08±10.15 years lower, respectively. Smoking (OR, 0.23), blood pressure ≥ 130/85mmHg (OR, 0.11), altered baseline blood glucose (OR, 0.45), abdominal obesity (OR, 0.58), triglycerides ≥ 150mg/dL (OR, 0.17), and metabolic syndrome (OR, 0.13) decreased the probability of HVA estimated by HA; an active lifestyle (OR, 1.84) and elevated high-density lipoprotein-cholesterol (OR, 3.26) increased the probability of HVA estimated by HA. Smoking (OR, 0.45), blood pressure ≥ 130/85mmHg (OR, 0.26), altered baseline blood glucose (OR, 0.42), and metabolic syndrome (OR, 0.40) decreased the probability of HVA estimated by VA; abdominal obesity (OR, 1.81) had the opposite effect.HA and VA were 3 years lower than the chronological age. HA was associated with tobacco consumption, physical activity, and the components of metabolic syndrome. Meanwhile, VA was associated with tobacco consumption, blood pressure, waist circumference, and altered baseline glycemia.http://www.clinicaltrials.gov. Identifier: NCT02623894. |
| Databáze: | OpenAIRE |
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