Predictors of mortality among patients enrolled on antiretroviral therapy in Aksum hospital, northern Ethiopia: a retrospective cohort study
| Autor: | Fisaha Haile, Kidane Tadesse, Neway Hiruy |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Adolescent Clinical Research Design Population lcsh:Medicine Viral diseases Global Health Social and Behavioral Sciences Cohort Studies Sociology Case fatality rate Death Rate medicine Electronic Health Records Humans Hospital Mortality lcsh:Science education Survival rate Retrospective Studies Demography education.field_of_study Acquired Immunodeficiency Syndrome Multidisciplinary Proportional hazards model business.industry Mortality rate lcsh:R Hazard ratio HIV Retrospective cohort study HIV diagnosis and management Middle Aged CD4 Lymphocyte Count Survival Rate Anti-Retroviral Agents Cohort Medicine Infectious diseases lcsh:Q Female Ethiopia Public Health business Research Article |
| Zdroj: | PLoS ONE PLoS ONE, Vol 9, Iss 1, p e87392 (2014) |
| ISSN: | 1932-6203 |
| Popis: | BACKGROUND: Since launching of antiretroviral (ART) treatment, the numbers of patients enrolled in to ART are increasing in many developing countries. But many studies done across Africa including Ethiopia on antiretroviral therapy programs have shown higher mortality at the first six months of treatment initiation. But the factors associated with this high mortality are poorly characterized. So this study aims to determine mortality and identify predictors of it among patients on ART. METHODS: Retrospective cohort study was employed among a total of 520 records of patients who were enrolled on antiretroviral therapy in Aksum hospital from September 2006 to August 2011. Baseline patient records were extracted from electronic and paper based medical records database and analysed using Kaplan Meier survival and Cox proportional hazard model to identify the independent predictors of mortality of patients on ART. RESULTS: A total of 46 (8.85%) deaths was observed giving an overall mortality rate of 3.2 per 100 person-years. The independent predictor of mortality identified for this cohort were haemoglobin level |
| Databáze: | OpenAIRE |
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