Hypercalcemia and Extensive Chest Metastasis of Vulvar Squamous Cell Carcinoma
| Autor: | Rui M.M. Victorino, Carlos Pires, Ernestina Natália Mota, Isabel Paulos Mesquita |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Vulvar Squamous Cell Carcinoma pulmonary metastasis of vulvar squamous cell carcinoma lcsh:Medicine Metastasis 03 medical and health sciences 0302 clinical medicine paraneoplastic hypercalcemia Keratinizing Squamous Cell Carcinoma Squamous cell carcinoma of the vulva Biopsy Internal Medicine medicine 030219 obstetrics & reproductive medicine Lung integumentary system medicine.diagnostic_test business.industry lcsh:R Mediastinum Articles medicine.disease female genital diseases and pregnancy complications stomatognathic diseases medicine.anatomical_structure 030220 oncology & carcinogenesis Concomitant Vulvar Carcinoma Radiology business |
| Zdroj: | European Journal of Case Reports in Internal Medicine (2019) European Journal of Case Reports in Internal Medicine |
| ISSN: | 2284-2594 |
| DOI: | 10.12890/2019_001218 |
| Popis: | A 73-year-old woman with a diagnosis of vulvar carcinoma submitted to curative surgery 5 years previously, presented to the emergency department with prostration and vulvar haemorrhage. Although the gynaecological examination was unremarkable, she had a mass in the left chest wall and hypercalcemia. A CT scan of the thorax revealed a voluminous left hemithorax mass invading the mediastinum, lung, pleura and chest wall. Ultrasound-guided biopsy of the mass showed infiltration by a well-differentiated keratinizing squamous cell carcinoma (SCC). This case report describes an extremely rare metastatic pattern in vulvar SCC concomitant with paraneoplastic hypercalcemia. LEARNING POINTS Pulmonary metastasis of vulvar carcinoma with chest wall invasion should be included in the list of rare manifestations of squamous cell carcinoma. Hypercalcaemia is common in squamous cell carcinoma but rare in vulvar carcinoma, and is associated with a bad prognosis. |
| Databáze: | OpenAIRE |
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