Similar in vitro response of rat brain nerve terminals, colon preparations and COLO 205 cells to smoke particulate matter from different types of wood

Autor: Konstantin Paliienko, Mariia Korbush, Natalia Krisanova, Natalia Pozdnyakova, Arsenii Borysov, Alla Tarasenko, Artem Pastukhov, Marina Dudarenko, Lilia Kalynovska, Valeria Grytsaenko, Liudmyla Garmanchuk, Taisa Dovbynchuk, Ganna Tolstanova, Tatiana Borisova
Rok vydání: 2022
Předmět:
Zdroj: NeuroToxicology. 93:244-256
ISSN: 0161-813X
Popis: Major source of carbon-containing air born particular matter that significantly pollutes environment and provokes development of neuropathology is forest fires and wood combustion. Here, water-suspended smoke particulate matter preparations (SPs) were synthesized from birch, pine, poplar wood, and also birch bark and pine needles. Taking into account importance of the gut-brain communication system, SP properties were compared regarding their capability to modulate functioning of nerve terminals and gut cells/preparations. In cortex nerve terminals, poplar wood SP was more effective in decreasing uptake and increasing the extracellular levels of excitatory and inhibitory neurotransmitters L-[
Databáze: OpenAIRE