Monitoring influenza vaccine effectiveness using the national influenza surveillance system

Autor: Maria Graça Freitas, Carlos Matias Dias, Raquel Guiomar, Ausenda Machado, Baltazar Nunes
Rok vydání: 2014
Předmět:
Zdroj: European Journal of Public Health. 24
ISSN: 1464-360X
1101-1262
0213-9111
DOI: 10.1093/eurpub/cku161.033
Popis: Resumo da apresentação publicado em: Gac Sanit. 2015;29 (Supl):168. Disponível em: http://www.gacetasanitaria.org/es/vol-29-num-s/suplemento/congresos/X0213911115X24386/#II CONGRESO IBEROAMERICANO DE EPIDEMIOLOGÍA Y SALUD PÚBLICA Background: Flu vaccine composition is reformulated on a yearly basis. As such, the vaccine effectiveness (VE) from previous seasons cannot be considered for subsequent years, and it is necessary to monitor the VE for each season. This study (MonitorEVA- monitoring vaccine effectiveness) intends to evaluate the feasibility of using the national influenza surveillance system (NISS) for monitoring the influenza VE. Material and methods: Data was collected within NISS during 2004 to 2014 seasons. We used a case-control design where laboratory confirmed incident influenza like illness (ILI) patients (cases) were compared to controls (ILI influenza negative). Eligible individuals consisted on all aged individuals that consult a general practitioner or emergency room with ILI symptoms with a swab collected within seven days of symptoms onset. VE was estimated as 1- odds ratio of being vaccinated in cases versus controls adjusted for age and month of onset by logistic regression. Sensitivity analyses were conducted to test possible effect of assumptions on vaccination status, ILI definition and timing of swabs (
Databáze: OpenAIRE