Examination of levels pentraxin-3, interleukin-6, and C-reactive protein in rat model acute and chronic exercise
| Autor: | Melek Tunc-Ata, Günfer Turgut, Sebahat Turgut, Mukaddes Mergen-Dalyanoglu |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Physical Therapy Sports Therapy and Rehabilitation Muscle damage 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Training Orthopedics and Sports Medicine Chronic exercise Exercise physiology Interleukin 6 biology business.industry C-reactive protein Acute-phase protein Interleukin 030229 sport sciences Acute exercise 030104 developmental biology Endocrinology Myoglobin chemistry biology.protein Physical therapy Original Article Creatine kinase business |
| Zdroj: | Journal of Exercise Rehabilitation |
| Popis: | Different types of exercise occurs damage at the cellular level in the muscles. Muscle damage caused by exercise is determined creatine kinase, myoglobin, and increase in levels of acute phase protein and in-terleukin in blood. The purpose of this study was investigated the levels of pentraxin-3 (PTX-3), interleukin-6 (IL-6), and C-reactive protein (CRP) following acute and chronic exercising in rats. Twenty-six Wistar Albino male rats were divided in to three groups. A treadmill exercise was per-formed 3 days/week, 10 min/day for 1 week in acute groups. In chronic group, exercise performed 7 days/week, 60 min/day for 4 weeks. At the end of the experiment, plasma PTX-3, IL-6, and CRP levels were mea-sured. In current study, the PTX-3, IL-6, and CRP levels not observed statistically significant difference among control, acute, and chronic groups. The levels IL-6 and CRP were not significantly different between acute and chronic exercise groups (P > 0.05). However, the level of PTX-3 was found to be higher in the chronic group compared to the acute group (P < 0.05). The PTX-3 level increase on chronic exercise-induced muscle damage. Accorting to our results, we think that PTX-3 may have a protect role on muscle damage during chronic exercises. © 2017 Korean Society of Exercise Rehabilitation. |
| Databáze: | OpenAIRE |
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