Engineering Wired Life: Synthetic Biology for Electroactive Bacteria
| Autor: | Anna D. Corts, Sarah M. Glaven, Caroline M. Ajo-Franklin, Lin Su, Tanya Tschirhart, Jeffrey A. Gralnick, Lina J. Bird, Biki Bapi Kundu |
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| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
biology Bioelectric Energy Sources Biomolecule Biomedical Engineering Nanotechnology General Medicine biology.organism_classification Biochemistry Genetics and Molecular Biology (miscellaneous) Electron Transport Synthetic biology Electron transfer Electrical current chemistry Escherichia coli Extracellular Humans Redox active Synthetic Biology Electrodes Oxidation-Reduction Bacteria |
| Zdroj: | ACS Synthetic Biology. 10:2808-2823 |
| ISSN: | 2161-5063 |
| Popis: | Electroactive bacteria produce or consume electrical current by moving electrons to and from extracellular acceptors and donors. This specialized process, known as extracellular electron transfer, relies on pathways composed of redox active proteins and biomolecules and has enabled technologies ranging from harvesting energy on the sea floor, to chemical sensing, to carbon capture. Harnessing and controlling extracellular electron transfer pathways using bioengineering and synthetic biology promises to heighten the limits of established technologies and open doors to new possibilities. In this review, we provide an overview of recent advancements in genetic tools for manipulating native electroactive bacteria to control extracellular electron transfer. After reviewing electron transfer pathways in natively electroactive organisms, we examine lessons learned from the introduction of extracellular electron transfer pathways into Escherichia coli. We conclude by presenting challenges to future efforts and give examples of opportunities to bioengineer microbes for electrochemical applications. |
| Databáze: | OpenAIRE |
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