The oral toxicity of resorcinol during pregnancy: A case report
| Autor: | Yeltekin Demirel, Meral Cetin, Nihal Demirkoprulu, Bülent Duran, Sinan Gursoy, Bilge Gürelik |
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| Přispěvatelé: | Cumhuriyet Univ, Sch Med, Dept Obstet & Gynecol, TR-58140 Sivas, Turkey -- Cumhuriyet Univ, Sch Med, Dept Anesthesiol & Reanimat, Sivas, Turkey |
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
Adult
Health Toxicology and Mutagenesis Toxicology Fatal Outcome Oral administration Pregnancy medicine Bradycardia Humans Medication Errors Glasgow Coma Scale resorcinol Acne Fetus business.industry Cesarean Section Infant Newborn Metabolic acidosis Resorcinols Heart Rate Fetal medicine.disease poisoning Respiratory failure Anesthesia Toxicity Apgar Score Gestation Female pregnancy business |
| ISSN: | 1546-2161 |
| Popis: | WOS: 000224104600013 PubMed ID: 15462161 Resorcinol (1,3 benzenediol; m-dihydroxybenzene: resorcin) is a pharmaceutical agent used topically in dermatological treatments such as acne and related skin conditions. It could also be used in combination with the other acne treatment agents such as sulphur. It could be very hazardous if taken orally and there are limited reports on its toxic effects in human. The present work aimed to report a resorcinol poisoning case in which resorcinol was taken accidentally by a woman at 30 weeks of pregnancy. The major clinical findings were unconsciousness, drowsiness, and respiratory failure that required mechanical ventilation along with tonic-clonic seizures and hypothermia. In addition, the laboratory findings were leucocytosis, high bilirubin levels, severe metabolic acidosis, and green-colored urine. The fetus was considered dead 24 It after delivery; however, mother's prognosis was well with supportive management. It could be concluded that the basic approach to the patient with resorcinol poisoning should include the initial stabilization of immediate life-threatening problems and elimination of the toxin. This is the first report on resorcinol poisoning in pregnant women, indicating its major clinical and laboratory findings. |
| Databáze: | OpenAIRE |
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