Effect of Sodium Diclofenac on Microcirculation and Composition of the Lymph during Fever Reaction
| Autor: | F. I. Mukhutdinova, D. R. Tagirova |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Diclofenac Fever Stimulation Kinins Pharmacology General Biochemistry Genetics and Molecular Biology Microcirculation Interstitial space Animals cardiovascular diseases urogenital system Chemistry Anti-Inflammatory Agents Non-Steroidal Therapeutic effect General Medicine Diclofenac Sodium Metabolism Thermoregulation biological factors Rats stomatognathic diseases Immunology Female Kallikreins Lymph circulatory and respiratory physiology |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 139:287-289 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-005-0273-7 |
| Popis: | Therapeutic effect of sodium diclofenac during fever reaction is associated not only with specific modulation of thermoregulation, but also with the increase in the count of lymphocytes transported with the lymph into systemic circulation, stimulation of lymph microcirculation, and improvement of metabolism in the interstitial space. This preparation inhibited kininogenesis and stimulated degradation of kinins. Sodium diclofenac serves as a universal inhibitor of the kallikrein-kinin system. |
| Databáze: | OpenAIRE |
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