Hypoglycemic effects of Lagenaria siceraria, Cynodon dactylon and Stevia rebaudiana extracts
| Autor: | Somnath D. Bhinge, Poonam R. Sanap, Dheeraj S. Randive, Kiran P. Shejawal, Mangesh A. Bhutkar, Suhas A. Mane, Pranoti D. Patil |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Cynodon dactylon
Medicine (General) RM1-950 01 natural sciences 03 medical and health sciences 0302 clinical medicine R5-920 In vivo Drug Discovery Sugar biology Traditional medicine Chemistry Lagenaria Amylolysis kinetic biology.organism_classification Current analysis 030205 complementary & alternative medicine 0104 chemical sciences 010404 medicinal & biomolecular chemistry Stevia rebaudiana Hypoglycemic activity Lagenaria siceraria Hypoglycemic Effects Therapeutics. Pharmacology Herbal medicine |
| Zdroj: | Journal of HerbMed Pharmacology, Vol 8, Iss 1, Pp 51-55 (2019) |
| ISSN: | 2345-5004 |
| Popis: | Introduction: The aim of the current analysis was to judge the hypoglycemic action of the phyto-extracts of Lagenaria siceraria, Cynodon dactylon and Stevia rebaudiana using suitable in vitro approaches. Methods: The hypoglycemic activity of the phyto-material extracts was evaluated by employing various in-vitro methods namely glucose diffusion, amylolysis kinetics and glucose adsorption capacity. Results: The extracts of L. siceraria, C. dactylon and S. rebaudiana exhibited glucose dialysis retardation indices (GDRI) of 48.14%, 37.03% and 29.62%, respectively at 60 minutes which were reduced to 15.78%, 10.52% and 18.42%, respectively at 120 minutes. All the plant extracts used in the study adsorbed glucose and their adsorptions markedly enhanced with increase in sugar concentration. Conclusion: From the outcome of the assay it can be concluded that the extracts of L. siceraria, C. dactylon and S. rebaudiana have hypoglycemic activity as observed in various in-vitro assays. However, the beneficial actions require to be verified by adopting various in vivo techniques along with clinical trials for their efficient use as potential remedial moiety. |
| Databáze: | OpenAIRE |
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