Clinical Outcomes of Micropulse Laser Trabeculoplasty Compared to Selective Laser Trabeculoplasty at One Year in Open-Angle Glaucoma
Autor: | Tiffany A Chen, Yvonne Ou, Catherine Q. Sun, Michael S. Deiner |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Aging Open angle glaucoma Selective laser trabeculoplasty genetic structures medicine.medical_treatment Glaucoma open-angle glaucoma Neurodegenerative Eye 03 medical and health sciences 0302 clinical medicine Primary outcome Clinical Research Opthalmology and Optometry Ophthalmology medicine Glaucoma surgery selective laser trabeculoplasty Eye Disease and Disorders of Vision Original Research Glaucoma medication business.industry Neurosciences Clinical Ophthalmology Laser trabeculoplasty medicine.disease eye diseases micropulse laser trabeculoplasty Relative risk 030221 ophthalmology & optometry sense organs business 030217 neurology & neurosurgery |
Zdroj: | Clinical Ophthalmology (Auckland, N.Z.) |
ISSN: | 1177-5483 1177-5467 |
Popis: | Catherine Q Sun, Tiffany A Chen, Michael S Deiner, Yvonne Ou Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USACorrespondence: Catherine Q SunUCSF F.I. Proctor Foundation, 490 Illinois Street, Floor 2, San Francisco, CA 94143, USAEmail catherine.sun@ucsf.eduBackground: There is limited long-term data comparing selective laser trabeculoplasty (SLT) to the newer micropulse laser trabeculoplasty (MLT) using a laser emitting at 532 nm. In this study, we determine the effectiveness and safety of MLT compared to SLT.Design: Retrospective comparative cohort study.Participants: A total of 85 consecutive eyes received SLT and 43 consecutive eyes received MLT.Methods: Patients with open-angle glaucoma receiving their first treatment of laser trabeculoplasty were included. Exclusion criteria are prior laser trabeculoplasty, laser cyclophotocoagulation or glaucoma surgery, and follow-up of less than 1 year.Main Outcome Measures: The primary outcome was success at 1 year, defined as a reduction in intraocular eye pressure (IOP) by ≥ 20% from baseline or met prespecified target IOP with no additional glaucoma medication or subsequent glaucoma intervention.Results: Baseline IOP was 18.0 mmHg (95% CI=16.4– 19.5) in the MLT group on an average of 1.8 (95% CI=1.4– 2.2) glaucoma medications compared to 18.2 mmHg (95% CI=17.2– 19.3) for the SLT group on an average of 2.0 (95% CI=1.6– 2.3) medications. At 1-hour post-laser, the SLT group had more transient IOP spikes (MLT 5% vs SLT 16%, P=0.10). There was a trend toward increased success in the SLT group compared to MLT at 1 year (relative risk=1.4, 95% CI=0.8– 2.5, P=0.30).Conclusion and Relevance: Eyes had similar success after MLT compared to SLT at 1 year. Laser trabeculoplasty with either method could be offered as treatment with consideration of MLT in those eyes where IOP spikes should be avoided.Keywords: micropulse laser trabeculoplasty, selective laser trabeculoplasty, open-angle glaucoma |
Databáze: | OpenAIRE |
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