| Autor: |
Claudia, Sommerer, Iris, Schröter, Katrin, Gruneberg, Daniela, Schindler, Rouven, Behnisch, Christian, Morath, Lutz, Renders, Uwe, Heemann, Paul, Schnitzler, Anette, Melk, Andrea, Della Penna, Silvio, Nadalin, Klaus, Heeg, Stefan, Meuer, Martin, Zeier, Thomas, Giese |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Open forum infectious diseases. 9(7) |
| ISSN: |
2328-8957 |
| Popis: |
BackgroundInfectious complications are a major cause of morbidity and mortality after kidney transplantation.MethodsIn this transplant cohort study at the German Center of Infectious Diseases (DZIF), we evaluated all infections occurring during the first year after renal transplantation. We assessed microbial etiology, incidence rates, and temporal occurrence of these infections.ResultsOf 804 renal transplant recipients (65.2% male, 51 ± 14 years), 439 (54.6%) had 972 infections within the first year after transplantation. Almost half of these infections (47.8%) occurred within the first 3 months. Bacteria were responsible for 66.4% (645/972) of all infections, followed by viral (28.9% [281/972]) and fungal (4.7% [46/972]) pathogens. The urinary tract was the most common site of infection (42.4%). Enterococcus was the most frequently isolated bacterium (20.9%), followed by E. coli (17.6%) and Klebsiella (12.5%). E. coli was the leading pathogen in recipients ConclusionsRenal allograft recipients in Germany experience a high burden of infectious complications in the first year after transplantation. Bacteria were the predominating pathogen, followed by opportunistic infections such as cytomegalovirus. Microbial etiology varied between age groups, and resistant bacteria were identified in 10% of recipients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
|
Nepřihlášeným uživatelům se plný text nezobrazuje |
K zobrazení výsledku je třeba se přihlásit.
|
