Human papillomavirus association with head and neck cancers: understanding virus biology and using it in the development of cancer diagnostics
| Autor: | Strati, K., Lambert, P. F. |
|---|---|
| Přispěvatelé: | Strati, K. [0000-0002-2332-787X] |
| Rok vydání: | 2008 |
| Předmět: |
squamous cell carcinoma
Oncology genetic association viruses protein E7 protein E6 Disease Bioinformatics Diagnostic tools cancer diagnosis virus infection Medicine Head and neck cancer Head and neck virus replication E7 E6 virus diseases General Medicine protein function head and neck carcinoma protein protein interaction virus gene Molecular Medicine virus pathogenesis HPV Human papillomavirus medicine.medical_specialty review Biomedical Engineering Article Virus Wart virus stomatognathic system Internal medicine human neoplasms nonhuman virus carcinogenesis business.industry Biochemistry (medical) Cancer medicine.disease Head and neck squamous-cell carcinoma stomatognathic diseases business Biomarkers uterine cervix cancer |
| Zdroj: | Expert Opinion on Medical Diagnostics Expert Opin.Med.Diagn. |
| ISSN: | 1753-0067 1753-0059 |
| DOI: | 10.1517/17530059.2.1.11 |
| Popis: | The link between human papillomaviruses (HPVs) and human cervical cancers has long been established. However, HPVs are now being detected in another type of cancer not previously associated with this virus, head and neck squamous cell carcinoma (HNSCC). This review will focus on experimental data supporting the view that HPVs contribute to the etiology of a subset of HNSCC. The authors further put forth the argument that HPV-associated HNSCC deserves to be recognized as a distinct disease in the clinic and, as such, needs to be appropriately diagnosed. An overview of studies that have helped dissect the role of HPVs in HNSCC and that may be helpful in the development of new diagnostic tools for discriminating this type of HNSCC is provided. © 2008 Informa UK Ltd. 2 11 20 Cited By :4 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|