Transmission of canine influenza virus (H3N8) among susceptible dogs
| Autor: | Terri Lee Wasmoen, Huchappa Jayappa, Faris F Jirjis, Anna L. Tubbs, Nallakannu Lakshmanan, Muralidhar S. Deshpande |
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| Rok vydání: | 2009 |
| Předmět: |
Time Factors
Canine influenza Orthomyxoviridae Nose Microbiology Virus Influenza A Virus H3N8 Subtype Dogs Orthomyxoviridae Infections medicine Animals Dog Diseases Viral shedding Seroconversion Lung Communicable disease General Veterinary biology General Medicine medicine.disease biology.organism_classification Virology Virus Shedding Trachea Pneumonia Immunology Viral disease |
| Zdroj: | Veterinary microbiology. 144(3-4) |
| ISSN: | 1873-2542 |
| Popis: | Canine influenza virus (CIV) is an emerging pathogen that causes acute respiratory disease in dogs. As with any communicable disease, dog-to-dog transmission of CIV occurs when infected dogs come in contact with other susceptible dogs. We demonstrate that CIV transmission occurs readily from CIV-infected dogs to susceptible dogs following co-mingling. Four experimentally infected dogs were co-mingled with a group of eight CIV-negative dogs at 1 day post-infection and both groups were observed for CIV-associated respiratory disease. The onset of clinical signs, virus shedding, seroconversion, and appearance of lung lesions were observed earlier in experimentally infected dogs; however, the severity of the clinical signs and lung lesions were very similar in both groups. One hundred percent of the experimentally infected dogs and 75% of the contact-exposed dogs excreted virus in their nasal secretions. Additionally, 100% of experimentally infected dogs and 75% of the contact-exposed dogs exhibited varying degrees of pneumonia. Our study results demonstrate that CIV spreads readily from infected dogs to other susceptible dogs through direct contact. |
| Databáze: | OpenAIRE |
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