H1.0 C Terminal Domain Is Integral for Altering Transcription Factor Binding within Nucleosomes

Autor: Nathaniel L. Burge, Jenna L. Thuma, Ziyong Z. Hong, Kevin B. Jamison, Jennifer J. Ottesen, Michael G. Poirier
Rok vydání: 2023
Předmět:
Zdroj: Biochemistry. 61(8)
ISSN: 1520-4995
Popis: The linker histone H1 is a highly prevalent protein that compacts chromatin and regulates DNA accessibility and transcription. However, the mechanisms behind H1 regulation of transcription factor (TF) binding within nucleosomes are not well understood. Using
Databáze: OpenAIRE