Presumed Central Nervous System Whipple's Disease in a Child: Case Report
| Autor: | Clark L. Carrol, Barry R. Tharp, Hannes Vogel, Tina Q. Tan, Sheldon L. Kaplan |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Male
Microbiology (medical) Brain Diseases Pediatrics medicine.medical_specialty Pathology business.industry Whipple Disease Central nervous system Signs and symptoms Disease medicine.disease Central nervous system disease Infectious Diseases medicine.anatomical_structure El Niño Child Preschool medicine Humans Whipple's disease business Pathological Follow-Up Studies |
| Zdroj: | Clinical Infectious Diseases. 20:883-889 |
| ISSN: | 1537-6591 1058-4838 |
| DOI: | 10.1093/clinids/20.4.883 |
| Popis: | Whipple's disease is a rare, chronic, multisystem illness that is pathologically characterized by the accumulation of macrophages in the involved tissue that have a positive periodic acid-Schiff reaction. It is typically seen in middle-aged white men, and only four cases involving persons younger than 15 years of age have been reported. CNS Whipple's disease without intestinal manifestations is rare; only six cases have been reported in the literature, all involving adults. We report the case of a young boy with clinical, laboratory, radiographic, and pathological signs and symptoms consistent with CNS Whipple's disease who responded to therapy with trimethoprimsulfamethoxazole. |
| Databáze: | OpenAIRE |
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