Epidemiology and Clinical Outcomes of Hospitalizations for Acute Respiratory or Febrile Illness and Laboratory-Confirmed Influenza Among Pregnant Women During Six Influenza Seasons, 2010–2016
| Autor: | Dan Riesel, Fatimah S. Dawood, Mark G. Thompson, Hannah Chung, Rebecca V. Fink, Deshayne B. Fell, Margaret L. Russell, Annette K. Regan, Shikha Garg, Nicola P. Klein, Jeffrey C. Kwong, Brandy E Wyant, Stephanie Booth, Avram Levy, Mark A. Katz, Allison L. Naleway |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Time Factors Adolescent Fever Respiratory Tract Diseases Global Health Cohort Studies Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy Interquartile range Intensive care Internal medicine Influenza Human Pandemic Epidemiology medicine Humans Immunology and Allergy 030212 general & internal medicine Retrospective Studies 030219 obstetrics & reproductive medicine business.industry Public health Respiratory infection Middle Aged medicine.disease Hospitalization Pneumonia Infectious Diseases Respiratory failure Female Seasons business |
| Zdroj: | The Journal of Infectious Diseases. 221:1703-1712 |
| ISSN: | 1537-6613 0022-1899 |
| Popis: | Background Pregnant women are at increased risk of seasonal influenza hospitalizations, but data about the epidemiology of severe influenza among pregnant women remain largely limited to pandemics. Methods To describe the epidemiology of hospitalizations for acute respiratory infection or febrile illness (ARFI) and influenza-associated ARFI among pregnant women, administrative and electronic health record data were analyzed from retrospective cohorts of pregnant women hospitalized with ARFI who had testing for influenza viruses by reverse-transcription polymerase chain reaction (RT-PCR) in Australia, Canada, Israel, and the United States during 2010–2016. Results Of 18 048 ARFI-coded hospitalizations, 1064 (6%) included RT-PCR testing for influenza viruses, 614 (58%) of which were influenza positive. Of 614 influenza-positive ARFI hospitalizations, 35% were in women with low socioeconomic status, 20% with underlying conditions, and 67% in their third trimesters. The median length of influenza-positive hospitalizations was 2 days (interquartile range, 1–4), 18% (95% confidence interval [CI], 15%–21%) resulted in delivery, 10% (95% CI, 8%–12%) included a pneumonia diagnosis, 5% (95% CI, 3%–6%) required intensive care, 2% (95% CI, 1%–3%) included a sepsis diagnosis, and Conclusions Our findings characterize seasonal influenza hospitalizations among pregnant women and can inform assessments of the public health and economic impact of seasonal influenza on pregnant women. |
| Databáze: | OpenAIRE |
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