Revival of favus in Japan caused by Trichophyton schoenleinii
Autor: | Takashi Mochizuki, Kohei Ogawa, Tomoyuki Iwanaga, Hideo Asada, Kentaro Iwasa, Hiroshi Tanabe, Hiroaki Azukizawa, Kazushi Anzawa |
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Rok vydání: | 2018 |
Předmět: |
Antifungal Agents
Luliconazole Tinea Favosa Dermatology Scutula law.invention Microbiology 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Japan Trichophyton law medicine Humans Internal transcribed spacer Polymerase chain reaction biology General Medicine Ribosomal RNA Middle Aged biology.organism_classification Staining Treatment Outcome chemistry 030220 oncology & carcinogenesis Vellus hair Terbinafine Female Hair Follicle medicine.drug |
Zdroj: | The Journal of dermatology. 46(4) |
ISSN: | 1346-8138 |
Popis: | Favus is a type of dermatophytosis known to produce yellow scutula around hair follicles. Most cases of this disease worldwide are infections of Trichophyton schoenleinii. Favus has rarely been reported in Japan throughout the last four decades, and T. schoenleinii has not been clinically isolated in any case during the period. Here, we report a case of favus of vellus hair observed in a 63-year-old Japanese woman. Fungal culture showed negative; however, we detected fungal elements in the crust and hair bulbs by Grocott staining. Pathogenic fungi were identified as T. schoenleinii by polymerase chain reaction-based DNA sequencing, targeting the internal transcribed spacer regions of the rRNA gene using the formalin-fixed, paraffin-embedded tissue sample. She was successfully treated with p.o. administration of terbinafine and topical application of luliconazole cream. |
Databáze: | OpenAIRE |
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