Acute Hepatitis Due to Agomelatine Use in Elderly Women with Depression: Case Series
| Autor: | Cheng-Chen Chang, Yi-Cheng Liao, Yu-An Chen, Yen-Jen Chen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Liver injury
medicine.medical_specialty business.industry Case Report medicine.disease Clinical trial Behavioral Neuroscience Psychiatry and Mental health Increased risk Internal medicine medicine Agomelatine Major depression Pharmacology (medical) Liver function Acute hepatitis Risk factor business Depression (differential diagnoses) medicine.drug |
| Zdroj: | Clinical Psychopharmacology and Neuroscience |
| ISSN: | 2093-4327 1738-1088 |
| Popis: | Although agomelatine may be associated with an increased risk of hepatotoxicity, the incidence rate of acute hepatitis seemed divergent between clinical trials and daily practice. Whether aging or gender is a risk factor in developing hepatotoxicity due to agomelatine is not clear. We present 3 older female cases with acute hepatitis occurring due to highly probable idiosyncratic drug-induced liver injury caused by agomelatine. From these cases, regular surveillance on liver function in the older women taking antidepressants would be of benefits. |
| Databáze: | OpenAIRE |
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