Normal percentage of CD56bright natural killer cells in young patients with a history of repeated unexplained implantation failure after in vitro fertilization cycles

Autor: Anna Mestice, Pantaleo Greco, Arcangelo Liso, Domenico Baldini, Michele Santodirocco, Piergiorgio Rosenberg, Maria Matteo, T. Falagario, Laura Castellana, Francesca Massenzio, Vincenzo Martino, Giorgina Specchia
Rok vydání: 2007
Předmět:
Zdroj: Fertility and Sterility. 88:990-993
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2007.01.028
Popis: Changes in endometrial leukocyte subpopulations and most of all in the percentage of uterine natural-killer cells (uNK), during the menstrual cycles, may have a pivotal role in the implantation process. An increase of activated NK cells (CD56dim CD16+ CD69+) in the peripheral blood of patients with a reduced rate of embryo implantation in IVF treatment has been reported elsewhere, but we found, by using flow cytometry, normal endometrial lymphocyte subpopulations in young patients with a history of repeated unexplained implantation failure who were undergoing IVF cycles for idiopathic infertility.
Databáze: OpenAIRE