Studies on the Chemical Composition of Lipopolysaccharide from Neisseria meningitidis Group B
| Autor: | Robert Z. Maigetter, Guadalupe A. Limjuco, Johanna Y. Zeltner, Dennis J. Carlo, Yashwant D. Karkhanis, J. J. King |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Lipopolysaccharides
chemistry.chemical_classification Lipopolysaccharide Neisseria meningitidis Fatty Acids Monosaccharides Heptose medicine.disease_cause Polysaccharide Microbiology Lipid A chemistry.chemical_compound chemistry Biochemistry Glucosamine Galactose medicine lipids (amino acids peptides and proteins) Acid hydrolysis |
| Zdroj: | Journal of General Microbiology. 104:187-191 |
| ISSN: | 0022-1287 |
| DOI: | 10.1099/00221287-104-2-187 |
| Popis: | SUMMARY: A lipopolysaccharide was isolated from Neisseria meningitidis group B by phenol/water extraction and purified by differential ultracentrifugation. This preparation exhibited endotoxic properties as shown by the limulus-lysate assay. Mild acid hydrolysis of the lipopolysaccharide yielded a lipid A fraction and a polysaccharide fraction. The lipid A fraction contained fatty acids, phosphorus and glucosamine. Analysis of the polysaccharide fraction revealed the presence of glucose, galactose, glucosamine, 2-keto-3-deoxyoctonic acid and phosphorus. There was no heptose. |
| Databáze: | OpenAIRE |
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