The Gut Microbial Architecture of Efficiency Traits in the Domestic Poultry Model Species Japanese Quail (Coturnix japonica) Assessed by Mixed Linear Models
| Autor: | Jörn Bennewitz, Markus Rodehutscord, Robin Wellmann, Amélia Camarinha-Silva, Daniel Borda-Molina, Solveig Vollmar |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Operational taxonomic unit
Zoology Coturnix Gut flora Quantitative trait locus QH426-470 Investigations quantitative traits Poultry 03 medical and health sciences Japanese quail RNA Ribosomal 16S Genetics Animals Molecular Biology Genetics (clinical) 030304 developmental biology 0303 health sciences biology Host (biology) Coturnix japonica 0402 animal and dairy science microbiability 04 agricultural and veterinary sciences Heritability biology.organism_classification hologenomic selection 040201 dairy & animal science Gastrointestinal Microbiome Metagenomics Trait Linear Models |
| Zdroj: | G3: Genes|Genomes|Genetics G3: Genes, Genomes, Genetics, Vol 10, Iss 7, Pp 2553-2562 (2020) |
| ISSN: | 2160-1836 |
| Popis: | It is well known that mammals and avian gut microbiota compositions are shaped by the host genomes and affect quantitative traits. The microbial architecture describes the impact of the microbiota composition on quantitative trait variation and the number and effect distribution of microbiota features. In the present study the gut microbial architecture of feed-related traits phosphorus and calcium utilization, daily gain, feed intake and feed per gain ratio in the domestic poultry model species Japanese quail were assessed by mixed linear models. The ileum microbiota composition was characterized by 16S rRNA amplicon sequencing techniques of growing individuals. The microbiability of the traits was on a similar level as the narrow sense heritability and was highly significant except for calcium utilization. The animal microbial correlation of the traits was substantial. Microbiome-wide association analyses revealed several traits associated and highly significant microbiota features, both on the bacteria genera as well as on the operational taxonomic unit level. Most features were significant for more than one trait, which explained the high microbial correlations. It can be concluded that the traits are polymicrobial determined with some microbiota features with larger effects and many with small effects. The results are important for the development of hologenomic selection schemes for feed-related traits in avian breeding programs that are targeting the host genome and the metagenome simultaneously. |
| Databáze: | OpenAIRE |
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