Supplementary Figure 1 from 10D1F, an Anti-HER3 Antibody That Uniquely Blocks the Receptor Heterodimerization Interface, Potently Inhibits Tumor Growth Across a Broad Panel of Tumor Models
Autor: | Jerome D. Boyd-Kirkup, Piers J. Ingram, Konrad H. Paszkiewicz, Eric Ng, Zhihao Wu, Siyu Guan, Marvin M. Taguiam, Vicente Sancenon, Dipti Thakkar |
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Rok vydání: | 2023 |
Popis: | 10D1F parental antibody, 10D1P, binds with high affinity and specificity to a species-conserved epitope on HER3, and Class 1 and Class 2 HER3 antibodies show different HER3 binding profiles in presence and absence of NRG1 |
Databáze: | OpenAIRE |
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