Human papillomavirus genotype distribution of genital keratotic lesions

Autor:	Seol Hwa Seong, Sun Mun Jeong, Jang Hwan Jung, Do Ik Kwon, Ji Yun Jang, Joon Hee Kim, Jong Bin Park, Jae Woo Baek, Kee Suck Suh, Min Soo Jang
Rok vydání:	2022
Předmět:	Genotype Condylomata Acuminata Papillomavirus Infections Carcinoma Squamous Cell Humans Dermatology Genitalia Alphapapillomavirus Keratosis Seborrheic Papillomaviridae Precancerous Conditions
Zdroj:	The Australasian journal of dermatologyREFERENCES. 63(3)
ISSN:	1440-0960
Popis:	Genital keratotic lesions include bowenoid papulosis (BP), which histologically resembles squamous cell carcinoma in situ containing high-risk HPV, condyloma acuminatum (CA) that is a genital wart containing mostly low-risk HPV, and genital seborrheic keratosis (GSK), which is a benign epidermal tumour lacking a clear etiologic relationship with HPV. This study compared HPV genotype distributions among BP, CA and GSK and revealed that BP and GSK were related to high-risk HPV whereas CA was related to low-risk HPV. It is plausible that GSK is a distinct epidermal tumour often related to high-risk HPV rather than merely a senescent form of CA considering the overall discrepancy in the frequency distribution of HPV genotypes along with histopathological differences, and the detection of high-risk HPV in GSK alerts physicians to consider more active treatment and continued follow-ups.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d006ee43ddd1cb73f0538a2748cdbb6 https://pubmed.ncbi.nlm.nih.gov/35545860 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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