Synthesis and surface modification of polyurethanes with chitosan for antibacterial properties
| Autor: | Filiz Kara, Nesrin Hasirci, Eda Ayse Aksoy, Serpil Aksoy, Zehra Nur Yuksekdag |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Staphylococcus aureus
Polymers and Plastics Surface Properties Polyurethanes Drug Evaluation Preclinical Microscopy Atomic Force Bacterial Adhesion Chitosan chemistry.chemical_compound Polymer chemistry Materials Chemistry Polyurethane Polypropylene biology Chemistry Photoelectron Spectroscopy Organic Chemistry biology.organism_classification Anti-Bacterial Agents Covalent bond Pseudomonas aeruginosa Surface modification Antibacterial activity Hydrophobic and Hydrophilic Interactions Ethylene glycol Bacteria Nuclear chemistry |
| Zdroj: | Carbohydrate Polymers. 112:39-47 |
| ISSN: | 0144-8617 |
| Popis: | Surface modification and providing antibacterial properties to the materials or devices are getting great attention especially in the last decades. In this study, polyurethane (PU) films were prepared by synthesizing them in medical purity from toluene diisocyanate and polypropylene ethylene glycol without using any other ingredients and then the film surfaces were modified by covalent immobilization of chitosan (CH) which has antibacterial activity. CH immobilized PU films (PU-CH) were found to be more hydrophilic than control PU films. Electron Spectroscopy for Chemical Analysis (ESCA) and Atomic Force Microscopy (AFM) analyses showed higher nitrogen contents and rougher surface topography for PU-CH compared to PU films. Modification with CH significantly increased antibacterial activity against Gram positive (Staphylococcus aureus) and Gram negative (Pseudomonas aeruginosa) bacteria. It was observed that the number of bacteria colonies were less about 10(2)-10(5) CFU/mL and number of attached viable bacteria decreased significantly after CH modification of PU films. (C) 2014 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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