A Special Case of Bilateral Ovarian Metastases in a Woman with Papillary Carcinoma of the Thyroid

Autor: P Viacava, Sandra Brogioni, E Macchia, Luca Tomisti, E Martino
Rok vydání: 2007
Předmět:
Zdroj: Experimental and Clinical Endocrinology & Diabetes. 115:397-400
ISSN: 1439-3646
0947-7349
Popis: Papillary thyroid carcinoma is a slow growing tumor with low metastatic potential. The most frequent sites of distant metastases are lung and bone; less frequent sites are brain, liver, kidney, and skin. Ovarian metastases from papillary thyroid carcinoma are exceptional. We describe a case of bilateral ovarian metastases from a papillary thyroid carcinoma associated with autoimmune thyroiditis in a 38-year-old woman who underwent thyroidectomy and cervical lymph-node dissection 7 years before, followed by 948 mCi of 131I. A primary ovarian cancer could be excluded by the typical pathological aspects of a papillary thyroid carcinoma in a context of an aggressive form of thyroid cancer. On the other hand, the clinical history and the absence of normal thyroid epithelium and teratomatous components could exclude a papillary thyroid carcinoma arising in struma ovarii. This is a singular case of papillary thyroid carcinoma metastasizing to the ovary, combined with an autoimmune thyroiditis.
Databáze: OpenAIRE