The relationship between growth of atherosclerotic plaques, variant angina and sudden death
| Autor: | Gaetano Thiene, Pietro Maiolino, Domenico Corrado, Gianfranco Buja, Attilio Pantaleoni |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Angina Pectoris
Variant Male medicine.medical_specialty Coronary Disease Coronary Artery Disease Anterior Descending Coronary Artery Sudden death Muscle Smooth Vascular Angina Coronary artery disease Death Sudden Electrocardiography Internal medicine medicine Humans Coronary atherosclerosis business.industry Fibrous cap Arrhythmias Cardiac Middle Aged medicine.disease Coronary Vessels Coronary arteries medicine.anatomical_structure Coronary vasospasm Electrocardiography Ambulatory Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | International Journal of Cardiology. 26:361-367 |
| ISSN: | 0167-5273 |
| DOI: | 10.1016/0167-5273(90)90095-m |
| Popis: | Clinico-pathological findings are described in two patients with typical variant angina who died suddenly during an ischemic attack. In both cases, detailed pathologic examination of the coronary arteries disclosed severe focal atherosclerosis of the anterior descending coronary artery. The only distinctive histological finding was new intimal proliferation of smooth muscle cells enmeshed within mucoid substance, superimposed on the old fibrous cap of the plaque. These findings agree with experimental and clinical data which suggest that coronary vasospasm may be related to growth of atherosclerotic plaques. This study provides histological evidence that progression of an atherosclerotic plaque may underlie variant angina and sudden death. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|