Safety, efficacy and long-term durability of endovascular therapy for carotid artery disease: the tailored-Carotid Artery Stenting Experience of a single high-volume centre (tailored-CASE Registry)
| Autor: | Maria Cristina Barattoni, Fausto Castriota, Raffaella Manetti, Alberto Cremonesi, Luigi Tavazzi, Luca Ghetti, Armando Liso, Alessandro Furgieri, Barbara Spagnolo, Shane Gieowarsingh |
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| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Time Factors medicine.medical_treatment Kaplan-Meier Estimate Risk Assessment Asymptomatic Disease-Free Survival Risk Factors Carotid artery disease Odds Ratio medicine Humans Carotid Stenosis Prospective Studies Registries Prospective cohort study Stroke Aged Aged 80 and over Chi-Square Distribution Vascular disease business.industry Mortality rate Angioplasty Stent Middle Aged medicine.disease Surgery Logistic Models Treatment Outcome Italy Stents medicine.symptom Carotid stenting Cardiology and Cardiovascular Medicine business |
| Zdroj: | EuroIntervention. 5:589-598 |
| ISSN: | 1774-024X |
| DOI: | 10.4244/eijv5i5a95 |
| Popis: | Aims: We aimed to determine the success, safety and long-term durability of carotid artery stenting (CAS) in stroke prevention for all-comers managed with mandatory neuroprotection and a tailored-approach to intervention. Methods and results: From our CAS registry (beginning July 1997) all procedures up to September 2007 with intention-to-treat by stenting under distal filter or proximal occlusion neuroprotection devices were analysed (N=1523 ; mean age 72 years [237 ≥80 years, 15.5%]). Indications included symptomatic stenoses ≥50% (366, 24.1%) and asymptomatic stenoses ≥80% (1157, 75.9%). CAS success was 99.6% and the 30-day all-stroke/death rate was 1.5% (minor stroke 11 [0.7%], major stroke 8 [0.5%], death 5 [0.3%]). The risk was 1.2% for asymptomatic patients and 2.7% for symptomatic patients (p=0.042). Regarding octogenarians this risk was 2.1% versus 1.5% for patients ≤79 years (p=0.47). Symptomatic octogenarians had a higher risk than other groups (OR 3.9, 95% Cl 1.06 to 14.0): asymptomatic |
| Databáze: | OpenAIRE |
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