Alterations in renal stone risk factors after space flight
Autor: | Peggy A. Whitson, Charles Y.C. Pak, Nitza M. Cintron, Robert A. Pietrzyk |
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Rok vydání: | 1993 |
Předmět: |
Adult
Male medicine.medical_specialty Time Factors Chemical Phenomena Extraterrestrial Environment Urology Physiology Urine chemistry.chemical_compound Kidney Calculi Sex Factors Risk Factors medicine Humans Hypercalciuria Risk factor Kidney business.industry Chemistry Physical Space medicine Middle Aged Space Flight medicine.disease Surgery medicine.anatomical_structure chemistry Uric acid Kidney stones Female business Hypocitraturia |
Zdroj: | The Journal of urology. 150(3) |
ISSN: | 0022-5347 |
Popis: | Exposure to the microgravity environment of space produces a number of physiological changes of metabolic and environmental origin that could increase the potential for renal stone formation. Metabolic, environmental and physicochemical factors that influence renal stone risk potential were examined in 24-hour urine samples from astronauts 10 days before launch and on landing day to provide an immediate postflight assessment of these factors. In addition, comparisons were made between male and female crewmembers, and between crewmembers on missions of less than 6 days and those on 6 to 10-day missions. Results suggest that immediately after space flight the risk of calcium oxalate and uric acid stone formation is increased as a result of metabolic (hypercalciuria, hypocitraturia, pH) and environmental (lower urine volume) derangements, some of which could reflect residual effects of having been exposed to microgravity. |
Databáze: | OpenAIRE |
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